Our new Obvious+ tissue clearing system is the only technique that delipidates samples without any adjust in morphology and with small influence on structural integrity.

Megatome is a vibrating microtome made to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits high-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue injury and data reduction.

Antibodies may well acquire months to diffuse by only some millimeters of tissue, that has a steep labeling gradient from floor to Main.

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SE uses a rotational electric powered industry to disperse remarkably electromobile molecules (for example antibodies or surfactant micelles) during a porous sample without having detrimental electrically billed constructions throughout the tissue. This permits 2-4 working day clearing of megatomi.com intact organs,

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Megatome is actually a novel microtome that allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue harm and data loss.

eFLASH is actually a speedy tissue labeling method which allows for uniform entire-organ staining in twenty rounds of labeling.

The SmartSPIM mild sheet microscope presents unparalleled resolution and acquisition pace throughout intact tissue volumes, even though its modular design means that you can upgrade and customise person parts.

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Protect avoids the variability of hydrogel embedding and the information reduction from PFA preservation, preserving specimens for many rounds of processing.

Leverage the Distinct+ tissue clearing approach, in conjunction with eFLASH and patented stochastic electrotransport systems, to rapidly distinct and label complete organs. Critical highlights and options include:

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